Scientific Papers

  • Hüls, D, Storchova, Z and Niessing, D
    Posttranslational modifications regulate assembly of the early spindle-orientation complex in yeast.
    J Biol Chem. 287(20): 16238-16245 (2012).

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  • Heym G.R. and Niessing, D
    Principles of mRNA transport in yeast. (Review)
    Cell Mol Life Sci. 69(11): 1843-1853 (2012). 

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  • Jansen, R-P and Niessing, D
    Assembly of mRNA-protein complexes for directional mRNA transport in eukaryotes - an overview. (Review; Special Issue on "Proteins involved in post-transcriptional control of gene expression")
    Current Protein & Peptide Science. In press (2012).

  • Aumiller V, Graebsch A, Kremmer E, Niessing, D, and Förstemann K
    Drosophila Pur-alpha binds to trinucleotide-repeat containing cellular RNAs and translocate to the early oocyte.
    RNA Biology 9(5): pp (2012).

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  • Müller, M.*, Heym, R.*, Mayer, A., Kramer, K., Schmid, M., Cramer, P., Urlaub, H., Jansen, R.P., Niessing, D.

    A cytoplasmic complex mediates specific mRNA recognition and localization in yeast.
    PLoS Biology 9(4): e1000611 (2011).    *equal contribution

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  • Niessing, D.:
    RNA-binding proteins in fungi and their role in mRNA localization.
    Chapter in RNA-BINDING PROTEINS, edited by L. Zdravko. Landes Bioscience and Springer Science (2011).

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  • Editor's Pick on Müller et al. PLoS Biol. 2011 by R. Robinson:
    A two-step process gets mRNA loaded and ready to go. PLoS Biology. 9(4) e1001047 (2011).

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  • Heuck, A., Fekta, I., Brewer, D.N., Hüls, D., Munson, M., Jansen, R.-P., Niessing, D.:

    The structure of the Myo4p globular tail and its function in ASH1 mRNA localization.

    J. Cell Biol. 189: 497-510 (2010).

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  • Graebsch, A., Roche, S., Kostrewa, D., Söding, J., Niessing, D.:
    Of Bits and Bugs - on the use of 
bioinformatics and a bacterial crystal structure to solve a eukaryotic repeat protein structure
.
    PLoS ONE 5 (10): e13402 (2010).

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  • Graebsch, A., Roche, S., Niessing, D.:
    X-ray structure of Pur-alpha reveals a Whirly-like fold 
and an unusual nucleic-acid binding surface.

    Proc. Natl. Acad. Sci. USA. Direct submission: 106: 18521-18526 (2009).

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  • Müller, M., Richter, K., Heuck, A., Kremmer, E., Buchner, J., Jansen, R.-P., Niessing, D.: 

    Formation of She2p Tetramers is Required for mRNA B indung, mRNP Assembly, and Localization.

    RNA. 15: 2002-2012 (2009).

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  • Du, T.G., Jellbauer, S., Müller, M., Schmid, M., Niessing, D., and Jansen, R.-P.:
    Nuclear transit 
of the RNA-binding protein She2p is required for translational control of localized ASH1 mRNA.
    EMBO Reports. 9: 781-787 (2008).

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  • Heuck, A., Du, T.-G., Jellbauer, S., Richter, K., Kruse, C., Jaklin, S., Müller, M., Buchner, J.,
Jansen, R.-P., & Niessing, D.:
    Monomeric myosin V uses two binding regions for the 
assembly of stable translocation complexes.
    Proc. Natl. Acad. Sci. USA - Direct submission: 105: 19778-19783 (2007).

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  • Müller, M., Heuck, A. and Niessing, D.:
    Directional mRNA Transport in Eukaryotes: 
lessons from yeast. 

    Cell. Mol. Life Sci. 64: 171-180 (2007).

  • Niessing, D., Zenklusen, D., Hüttelmaier, S., Singer, R.H. and Burley, S.K.:
    She2p is a 
Novel RNA-Binding Protein with a Basic Helical Hairpin Motif.
    Cell 119: 491-502 (2004).

  • Niessing, D.*, Blanke, S.* & Jäckle, H.:
    Bicoid associates with the 5’cap-bound 
complex of caudal mRNA and represses translation. 

    Genes & Dev. 16: 2576-2582 (2002).   *equal contribution

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  • Niessing, D., Driever, W., Sprenger, F, Taubert, H., Jäckle, H. & Rivera-Pomar, R.: 

    Homeodomain position 54 specifies transcriptional versus translational control by Bicoid.

    Mol. Cell 5: 395-401 (2000).

  • Niessing, D., Dostatni, N., Jäckle, H. and Rivera-Pomar, R.:
    Sequence interval within 
the PEST domain of Bicoid is important for translational repression of caudal mRNA 
in the anterior region of the Drosophila embryo. 

    EMBO J. 18: 1966-1973 (1999).

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  • Niessing, D., Rivera-Pomar, R., La Rosée, A., Häder, T., Schöck, F., Purnell, B.A. &
    Jäckle H.:
    A Cascade of Transcriptional Control Leading to Axis Determination in Drosophila. (1997)
    J. Cell. Physiol. 173: 162-167.

  • Rivera-Pomar, R., Niessing, D., Schmidt-Ott, U., Gehring, W.J. & Jäckle, H.
    RNA binding and translational suppression by bicoid.
    Nature 379: 746-749 (1996).

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